In stock

Selank 10mg

£14.50

Selank is a specialised synthetic heptapeptide developed for advanced scientific exploration of GABAergic modulation, neuropeptide signalling, and stress-response pathways, frequently studied in models of anxiolytic activity, immune modulation, and neuroplasticity.

Batch tested Purity: ≥ 98% (HPLC, typical)
CAS Number: 129954-34-3
Molecular Formula: C₃₃H₅₇N₁₁O₉
Amino Acid Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)

Available: In stock Category: Peptides Tag: 10 MG

Description

SELANK

Synonyms / Designations: Selank, Thr–Lys–Pro–Arg–Pro–Gly–Pro
CAS Number: 129954-34-3
Molecular Formula: C33H57N11O9
Molecular Weight: ~751.9 g/mol
Peptide Length: 7 amino acids
Peptide Type: Synthetic neuropeptide analogue
Purity: ≥ 99 % (HPLC, typical)
Appearance: White to off-white lyophilised powder
Pack Size: 5 mg (typical)
Storage: Desiccated, protected from light, stored at –20 °C or below
Solubility: Soluble in water and buffered aqueous solutions

Description & Mechanism

Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide tuftsin, modified to enhance stability and suitability for experimental investigation. It has been developed as a research tool for studying neuropeptide signalling, neuroimmune interactions, and central nervous system regulatory pathways.

In biochemical and cellular research systems, Selank has been examined for its influence on neuronal signalling pathways, including modulation of neurotransmitter systems and stress-response–associated signalling cascades. Experimental models often investigate its effects on gene expression, neuroimmune communication, and peptide–receptor interactions. Observed molecular responses are dependent on experimental design, concentration, and model system.

Applications in Research

As a molecular probe for studying neuropeptide-mediated signalling pathways.
Investigation of neuroimmune interactions and CNS regulatory mechanisms.
In vitro and in vivo studies examining peptide stability and signalling behaviour.
Use as a reference compound in neurobiology and peptide signalling research.

Specifications Summary

Purity (HPLC): ≥ 99 %
Appearance: White to off-white lyophilised powder
Molecular Weight: ~751.9 g/mol
Peptide Type: Synthetic neuropeptide
Solubility: Water, buffered aqueous solutions
Storage: –20 °C, desiccated, protected from light
Pack Size: 5 mg

Handling, Reconstitution & Stability

Weigh under dry conditions; peptide is hygroscopic.
Reconstitute in sterile water or appropriate buffered aqueous solution.
Avoid vigorous agitation during dissolution.
Filter sterilize if required prior to use.
Aliquot and store reconstituted solutions at –20 °C or lower.
Avoid repeated freeze–thaw cycles.

Precautions & Notes

Experimental behaviour of Selank is influenced by neuronal model, receptor expression, peptide concentration, and exposure duration.
Buffer composition, pH, and ionic strength may affect peptide stability.
Appropriate controls are recommended.
Intended strictly for laboratory research use.

References

Myasoedov N.F. et al. Tuftsin-derived peptides and neuroimmune regulation. Journal of Peptide Science, 2001.
https://pubmed.ncbi.nlm.nih.gov/11455544/

Ashmarin I.P. et al. Regulatory neuropeptides in central nervous system function. Neuroscience and Behavioral Physiology, 2005.
https://pubmed.ncbi.nlm.nih.gov/16059633/

Zozulya A.A. et al. Neuropeptide Selank and stress-related signalling. Bulletin of Experimental Biology and Medicine, 2010.
https://pubmed.ncbi.nlm.nih.gov/20820850/

Keywords: Selank, Synthetic Neuropeptide, Neuroimmune Signalling, CNS Regulation